Notice of Funding Opportunity for Pre-clinical and Early Stage Clinical Development of Drug Candidates for Alzheimer's Disease

National Institutes of Health

Description

This grant provides funding for developing therapies, which includes activities like improving drug compounds (medicinal chemistry), studying how drugs are processed in the body (pharmacokinetics, absorption, distribution, metabolism, excretion), assessing safety (toxicology), testing effectiveness in animals, creating biomarkers to track treatment effects, and preparing drugs according to manufacturing standards. It also covers studies required to start human testing and initial Phase I cli…

Grant recipients will receive funding for therapy development activities, such as medicinal chemistry, pharmacokinetics, absorption, distribution, metabolism, excretion, toxicology, efficacy in animal models, development of biomarkers for target engagement, formulation development, chemical synt…

Source

Grant ID

PAR-25-297

Agency

National Institutes of Health

Subcategory/Subagency

National Institute on Aging

Key Dates

Opportunity Released

December 4, 2024

Eligibility

The following categories of applicants are invited to apply:

  • Higher Education Institutions (Public/State-Controlled)
  • Higher Education Institutions (Private)
  • Nonprofits (Other than Institutions of Higher Education) with 501(c)(3) IRS status
  • Nonprofits (Other than Institutions of Higher Education) without 501(c)(3) IRS status
  • Small Businesses
  • For-Profit Organizations (Other than Small Businesses)
  • State Governments
  • County Governments
  • City or Township Governments
  • Special District Governments
  • Local Governments
  • Indian/Native American Tribal Governments (Federally Recognized)
  • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Eligible Agencies of the Federal Government
  • U.S. Territories or Possessions
  • Independent School Districts
  • Public Housing Authorities/Indian Housing Authorities
  • Native American Tribal Organizations (other than Federally recognized tribal governments)
  • Faith-based or Community-based Organizations
  • Regional Organizations
Additional Eligibility Information
Foreign/Non-domestic entities (Foreign Organizations) are NOT eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply, and foreign components (as defined in the NIH Grants Policy Statement) are allowed. Eligible Individuals (PD/PI): Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research may serve as PD/PI. For multiple PD/PI applications, follow the Multiple PD/PI Policy and Application Guide instructio…
Awards & Funding

Award Ceiling

$1.5M

Funding Amount

~$1.5M

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