Notice of Funding Opportunity for Alzheimer's Disease and Related Dementias Clinical Trials

National Institutes of Health

Description

This grant opportunity focuses on supporting early-stage clinical trials for new treatments targeting Alzheimer's disease and related dementias. It combines initial phase 1 and early phase 1b/2a trials into one process. Eligible interventions should target mechanisms other than amyloid and tau proteins and aim to improve cognitive and/or neuropsychiatric symptoms across different stages of the disease. Applications need to include criteria for assessing safety and tolerability to determine w…

This NOFO aims to streamline the early-stage evaluation of promising pharmacological interventions for Alzheimer's disease and related dementias by bundling phase 1 and phase 1b/phase 2a clinical trials. The interventions must engage non-amyloid/non-tau mechanisms and address cognitive and/or ne…

Source

Grant ID

PAR-25-226

Agency

National Institutes of Health

Subcategory/Subagency

National Institute on Aging

Key Dates

Opportunity Released

November 22, 2024

Eligibility

The following categories of applicants are invited to apply:

  • Regional Organizations
  • Eligible Agencies of the Federal Government
  • U.S. Territory or Possession
  • Independent School Districts
  • Public/State Controlled Institutions of Higher Education
  • Private Institutions of Higher Education
  • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Small Businesses
  • For-Profit Organizations (Other than Small Businesses)
  • Local Governments
  • State Governments
  • County Governments
  • City or Township Governments
  • Special District Governments
  • Indian/Native American Tribal Governments (Federally Recognized)
  • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Public Housing Authorities/Indian Housing Authorities
  • Native American Tribal Organizations (other than Federally recognized tribal governments)
  • Faith-based or Community-based Organizations
  • Non-domestic (non-U.S.) components of U.S. Organizations
  • Foreign components (as defined in the NIH Grants Policy Statement) are allowed
  • Non-domestic (non-U.S.) Entities (Foreign Organizations)
Additional Eligibility Information
- Foreign organizations are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. - Required registrations (must be completed prior to submission; can take 6+ weeks): System for Award Management (SAM) with annual renewal (domestic orgs receive/maintain CAGE code); NCAGE code required for foreign organizations to register in SAM; Unique Entity Identifier (UEI) issued via S…
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