This grant encourages partnerships between transplant immunologists and gene editing specialists to use SCGE technology in transplants. The goal is to prevent rejection, achieve transplant tolerance, extend the lifespan of transplanted organs, and enhance their function. Studies should involve human tissues or animal models and include modifications that reduce immune response and improve transplant outcomes.

This Notice of Special Interest (NOSI) aims to stimulate multidisciplinary collaborations between transplant immunologists and gene editing experts to explore the use of SCGE technology in transplantation. The focus is on preventing or treating rejection, achieving transplant tolerance, prolongi… Show More