Scout | RFA-FD-25-017: Efficient and Innovative Natural History Studies for Rare Diseases

Description

This grant aims to fund innovative studies that explore the progression of rare diseases with unmet medical needs. The goal is to gather high-quality data to fill knowledge gaps and overcome obstacles in developing medical products for these diseases. By doing so, it seeks to have a significant impact on the understanding and treatment of one or multiple rare diseases, and aid the development of new therapies.

The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data e…

Source

Grant ID

RFA-FD-25-017

Funding Source

Department of Health and Human Services ▸ National Institutes of Health

Key Dates

Letter of Intent Due

January 9, 2026

Application Due Date

February 10, 2026

Letter of Intent Due

January 7, 2028

Application Due Date

February 8, 2028

Eligibility

The following categories of applicants are invited to apply:

Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
Small Businesses
For-Profit Organizations (Other than Small Businesses)
Local Governments
State Governments
County Governments
City or Township Governments
Special District Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Governments
U.S. Territory or Possession
Independent School Districts
Public Housing Authorities/Indian Housing Authorities
Native American Tribal Organizations (other than Federally recognized tribal governments)
Faith-based or Community-based Organizations
Regional Organizations
Non-domestic (non-U.S.) Entities (Foreign Organizations)
Non-domestic (non-U.S.) components of U.S. Organizations

Additional Eligibility Information

- Foreign eligibility: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. - Required registrations (must be completed and maintained before submission; failure to complete on time is not a valid reason for late submission): • SAM (System for Award Management) active registration with annual renewal; domesti…

Awards & Funding

Award Ceiling

$600,000

Award Floor

$150,000

Funding Amount

Discretionary

Links

Documents

Full Funding Opportunity Announcement

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