Efficient and Innovative Natural History Studies for Rare Diseases
Department of Health and Human Services
Description
This grant aims to fund innovative studies that explore the progression of rare diseases with unmet medical needs. The goal is to gather high-quality data to fill knowledge gaps and overcome obstacles in developing medical products for these diseases. By doing so, it seeks to have a significant impact on the understanding and treatment of one or multiple rare diseases, and aid the development of new therapies.
The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data e…
Source
Grant ID
RFA-FD-25-017
Agency
Department of Health and Human Services
Subcategory/Subagency
National Institutes of Health
Key Dates
Letter of Intent Due
January 9, 2026
Application Due Date
February 10, 2026
Letter of Intent Due
January 7, 2028
Application Due Date
February 8, 2028
Eligibility
The following categories of applicants are invited to apply:
- Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
- Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
- Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Federal Governments
- U.S. Territory or Possession
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
- Non-domestic (non-U.S.) Entities (Foreign Organizations)
- Non-domestic (non-U.S.) components of U.S. Organizations
Awards & Funding
Award Ceiling
$600,000
Award Floor
$150,000
Funding Amount
Discretionary
Documents
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