Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Department of Health and Human Services

Description

This grant opportunity seeks applications for exploratory projects aimed at tackling "undruggable" target classes in human diseases. Researchers should identify a disease-relevant target class that is currently difficult to treat and develop new methods or agents that selectively target these areas. The goal is to encourage innovative strategies to address these challenging targets, advancing the development of selective treatments for them.

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method …

Source

Grant ID

PAR-25-442

Agency

Department of Health and Human Services

Subcategory/Subagency

National Institutes of Health

Eligibility

The following categories of applicants are invited to apply:

  • City or township governments
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Private institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Public and State controlled institutions of higher education
  • Special district governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • State governments
  • Native American tribal governments (Federally recognized)
  • County governments
  • For profit organizations other than small businesses
  • Independent school districts
  • Small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Eligibility Information
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and U…
Awards & Funding

Total Funding

$1M

Funding Amount

Discretionary

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