Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Department of Health and Human Services

Description

The National Center for Advancing Translational Sciences, along with other NIH Institutes, plans to announce a funding opportunity to support research on "undruggable" target classes in challenging human diseases. The goal is to encourage innovative approaches to modulate targets that can't be addressed by existing therapies, leading to new methods or agents selective for these targets. The research should serve as a proof of concept and potentially be expanded to broader studies. "Undruggab…

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method …

Source

Grant ID

PAR-25-442

Agency

Department of Health and Human Services

Subcategory/Subagency

National Institutes of Health

Eligibility

The following categories of applicants are invited to apply:

  • County governments
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Private institutions of higher education
  • Small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Independent school districts
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Public housing authorities/Indian housing authorities
  • For profit organizations other than small businesses
Additional Eligibility Information
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and U…
Awards & Funding

Total Funding

$1M

Funding Amount

Discretionary

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