Notice of Funding Opportunity Purpose

National Institutes of Health

Description

The grant opportunity is designed to extend current U19 awards to support the initiation of first-in-human clinical trials involving genome editing. It is part of the NIH Somatic Cell Genome Editing program and specifically requires the inclusion of a clinical trial, differentiating it from the earlier funding opportunity RFA-RM-22-015.

The NOFO aims to expand the scope of existing U19 awards to include first in human genome editing clinical trials. This opportunity is part of the NIH Somatic Cell Genome Editing program and requires a clinical trial, unlike the previous RFA-RM-22-015.

Source

Grant ID

RFA-RM-24-008

Agency

National Institutes of Health

Subcategory/Subagency

Office of Strategic Coordination (Common Fund)

Key Dates

Opportunity Released

November 21, 2024

Eligibility

The following categories of applicants are invited to apply:

  • Limited competition: Only existing SCGE IND-enabling Studies of Somatic Genome Editing Therapeutic Leads recipient(s) — awardees of RFA-RM-22-015 (active U19 awards)
  • U.S. Federal Government — Eligible Agencies of the Federal Government
  • U.S. Territory or Possession
  • Independent School Districts
  • Public Housing Authorities/Indian Housing Authorities
  • Native American Tribal Organizations (other than Federally recognized tribal governments)
  • Faith-based or Community-based Organizations
  • Regional Organizations
  • Non-domestic (non-U.S.) components of U.S. Organizations (eligible)
Additional Eligibility Information
Limited competition: Eligibility is restricted to existing awardees under RFA-RM-22-015 (SCGE IND-enabling Studies of Somatic Genome Editing Therapeutic Leads) with active U19 awards. Foreign (non-U.S.) organizations are NOT eligible to apply. However, non-domestic (non-U.S.) components of U.S. organizations are eligible to apply, and foreign components (as defined in the NIH Grants Policy Statement) are allowed within applications. This NOFO (RFA-RM-24-008) requires a clinical trial and is int…
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