Notice of Funding Opportunity (NOFO) for Investigator-Initiated Single Site Clinical Trials

National Institutes of Health

Description

This grant opportunity invites applications for developing and executing single-site clinical trials initiated by researchers. It supports trials focused on efficacy, comparative effectiveness, and implementation research, with innovative designs like platform and adaptive trials encouraged. The trials may explore various therapeutic, behavioral, or prevention strategies, and must align with the NHLBI's research goals while meeting NIH's clinical trial criteria. The grant uses a two-phase, m…

This NOFO supports applications to develop and implement investigator-initiated single site clinical trials including efficacy, comparative effectiveness, pragmatic and/or implementation research clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian des…

Source

Grant ID

PAR-25-028

Agency

National Institutes of Health

Subcategory/Subagency

National Heart, Lung, and Blood Institute

Key Dates

Opportunity Released

December 11, 2024

Eligibility

The following categories of applicants are invited to apply:

  • Faith-based or Community-based Organizations
  • Regional Organizations
  • Foreign Organizations (Non-domestic, non-U.S. entities)
  • Non-domestic (non-U.S.) components of U.S. Organizations
  • Higher Education Institutions (Public/State-controlled)
  • Higher Education Institutions (Private)
  • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Small Businesses
  • For-Profit Organizations (Other than Small Businesses)
  • Local Governments (general)
  • State Governments
  • County Governments
  • City or Township Governments
  • Special District Governments
  • Indian/Native American Tribal Governments (Federally Recognized)
  • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Native American Tribal Organizations (other than Federally recognized tribal governments)
  • Federal Government Agencies (Eligible Agencies of the Federal Government)
  • U.S. Territories or Possessions
  • Independent School Districts
  • Public Housing Authorities/Indian Housing Authorities
Additional Eligibility Information
- Foreign/Non-domestic eligibility: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. - Required registrations (must be completed before submission; can take 6+ weeks): SAM (active, renewed at least annually; domestic orgs receive/maintain CAGE code); NCAGE (required for foreign organizations to register in …
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