Exploratory Clinical Trials of Investigational Agents for Neurological Disorders

National Institutes of Health

Description

This grant helps small businesses perform early-stage clinical trials for new treatments targeting neurological disorders. Successful applicants will receive support through the NeuroNEXT network, including coordination and data management assistance, along with help for recruiting and retaining participants at clinical sites.

This funding opportunity supports small businesses in conducting exploratory clinical trials for investigational agents related to neurological disorders. Successful applicants will gain access to the NeuroNEXT infrastructure, which includes support from the Clinical Coordinating Center and Data…

Source

Grant ID

PAR-25-133

Agency

National Institutes of Health

Subcategory/Subagency

National Institute of Neurological Disorders and Stroke

Key Dates

Application Window Closes

September 5, 2027

Opportunity Released

November 12, 2024

Open for Submission

November 12, 2024

Submission Deadline

September 5, 2027

Eligibility

The following categories of applicants are invited to apply:

  • United States Small Business Concerns (SBCs) – for‑profit, with a U.S. place of business, operating primarily in the U.S. or contributing to the U.S. economy; including affiliates, have no more than 500 employees
  • U.S. SBCs majority‑owned and controlled (>50%) by one or more U.S. citizens or permanent resident aliens; by other qualifying small businesses similarly owned; by an Indian tribe, Alaska Native Corporation (ANC), or Native Hawaiian Organization (NHO); or any combination of these (SBIR/STTR ownership pathway)
  • U.S. SBCs majority‑owned (>50%) by multiple venture capital operating companies (VCOCs), hedge funds, or private equity firms (SBIR‑only), provided no single such firm owns >50% unless that firm itself qualifies as a U.S. SBC majority‑owned and controlled by U.S. individuals
  • Joint ventures of eligible SBCs (each JV partner must independently meet an SBIR ownership pathway; and in any JV, foreign business entities must hold <50% participation)
Additional Eligibility Information
Only United States Small Business Concerns (SBCs) are eligible applicants for this NOFO (SBIR). Key requirements and restrictions: Organizational/ownership requirements - Organized for profit; place of business in the United States; operates primarily in the U.S. or makes a significant contribution to the U.S. economy (e.g., taxes, U.S. products/labor). - Size standard: Including affiliates, the concern has no more than 500 employees. - Permissible legal forms include proprietorship, partners…
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