This program offers funding for clinical trials that are driven by specific hypotheses and milestones. It is particularly supportive of high-risk clinical studies, which may include unique and non-standard approaches, such as using unapproved products or approved products for new uses. While not necessarily involving risk to participants, these studies tend to explore less conventional methods. The program also welcomes proposed mechanistic studies.

This program provides support for hypothesis-driven, milestone-driven clinical trials. Although clinical trials not considered high-risk may be proposed, this program encourages high-risk clinical studies. High-risk does not imply human subject or patient risk, but rather defines a study that co… Show More