Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Department of Health and Human Services
Description
What this funds
- Clinical research that gets rare diseases ready for efficient, well-designed clinical trials by:
- Validating or adapting biomarkers and clinical outcome assessments (COAs) so they’re fit-for-purpose in upcoming trials.
- Defining disease presentation and natural history to inform inclusion/exclusion criteria, stratification, timing of intervention, and sample size/power.
Who’s offering it
- NIH’s National Center for Advanci…
Attaining effective therapies for rare diseases is challenging due to their low prevalence resulting in fewer patients, clinicians, researchers, and resources compared to common diseases. This leads to gaps in our understanding of a rare disease's natural history, and a dearth of suitable biomar…
Source
Grant ID
PAR:PAR-25-450.html
Agency
Department of Health and Human Services
Similar opportunities
- Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Department of Health and Human Services
- Forecast for Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Department of Health and Human Services
- Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)
Department of Health and Human Services
- Development of Novel or Improved Infertility Technologies (R61/R33 Clinical Trial Optional)
Department of Health and Human Services
- Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
Department of Health and Human Services