Notice of Funding Opportunity for Biomarker Validation in Neurological and Neuromuscular Disorders

National Institutes of Health

Description

This grant supports projects focused on identifying unmet needs for biomarkers and their measurement methods, specifying one or two specific uses for the biomarkers. Applicants can work on optimizing the accuracy, precision, reportable range, and analytical sensitivity and specificity of detection methods across different sites and operators. It also involves establishing reference intervals and quality control procedures. While multi-site projects are encouraged, they are not mandatory.

Applicants must justify the unmet need for the biomarker(s) and measurement methods and specify one or two context(s) of use for the biomarker(s). Activities supported include optimizing and evaluating the accuracy, precision, reportable range, and analytical sensitivity and specificity of the d…

Source

Grant ID

PAR-24-098

Agency

National Institutes of Health

Subcategory/Subagency

National Institute of Neurological Disorders and Stroke

Program

SBIR

Key Dates

Opportunity Released

January 22, 2024

Open for Submission

January 22, 2024

Submission Deadline

June 25, 2026

Application Window Closes

June 25, 2026

Eligibility

The following categories of applicants are invited to apply:

  • U.S. Small Business Concerns (SBCs) organized for profit with a place of business in the United States (≤500 employees including affiliates) meeting SBA SBIR/STTR definitions
  • U.S. SBCs majority-owned and controlled (>50%) by U.S. citizens or permanent residents, or by other qualifying SBCs majority-owned/controlled by such individuals
  • U.S. SBCs majority-owned by Indian Tribes, Alaska Native Corporations (ANCs), or Native Hawaiian Organizations (NHOs), or wholly owned entities of such (SBIR/STTR)
  • U.S. SBCs majority-owned by multiple venture capital operating companies (VCOCs), hedge funds, or private equity firms (SBIR only; subject to SBA conditions – no single firm >50% unless itself qualifies as an SBC owned/controlled by U.S. individuals)
  • Joint ventures that qualify as U.S. SBCs, in which each entity meets SBIR/STTR ownership requirements; JV must have <50% participation by foreign business entities
Additional Eligibility Information
Only United States Small Business Concerns (SBCs) are eligible to apply. Key SBA SBIR/STTR eligibility requirements apply at the time of award for Phase I and Phase II: - Organized for profit; place of business located in the U.S.; primarily operates in the U.S. or makes a significant contribution to the U.S. economy (taxes, use of U.S. products/labor). - Legal forms may include sole proprietorship, partnership, LLC, corporation, joint venture, association, trust, or cooperative. For joint vent…
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